PREVALENCE OF MULTIDRUG RESISTANT BACTREIA FROM CLINICAL SAMPLES IN SPECIALIST HOSPITAL, SOKOTO

Abstract

The emergence of multidrug-resistant (MDR) bacteria poses a serious challenge to effective clinical treatment and public health. This study aimed to determine the prevalence and identify MDR bacterial isolates from clinical samples. A total of seventy-two (72) bacterial isolates were obtained and characterized using standard microbiological and biochemical methods. Antibiotic susceptibility testing was performed using the Kirby–Bauer disk diffusion technique, and the Multiple Antibiotic Resistance (MAR) index was calculated to assess antibiotic exposure. All isolate were confirmed and found to be pure, the highest resistance was seen in augmentin for E.coli, ciprofloxacin and ceptazidime for Staphylococcus aureus, Amoxicillin and augmentin for salmonella, Levofloxacin and Gentamycin for klebsiella, levofloxacin for Pseudomonas auroginosa. The critical MAR index was observed in Salmonella (0.75), followed by Klebsiella (0.74) and Escherichia coli (0.629), followed by Pseudomonas aeruginosa (0.55) and Staphylococcus aureus (0.486). This finding highlight the increasing prevalence of MDR bacteria and underscore the urgent need for effective antibiotic stewardship and infection control strategies in clinical settings.